601 Results for "

Daphniphyllum majus Müll. Arg.

" in MedChemExpress (MCE) Product Catalog:
Products (601)

601 Results for "Daphniphyllum majus Müll. Arg." in MCE Product Catalog:

20
20 Publications Verification
Cat. No.: HY-100742A
CAS No.: 2003234-63-5
Purity:  99.73%
(R)-GNE-140 is a potent inhibitor of lactate dehydrogenase (LDH) A, B and C, with IC50 values of 3, 5 and 5 nM against LDHA, LDHB, LDHC, respectively. (R)-GNE-140 blocks the conversion of pyruvate to lactate, reduces lactate production and histone lysine lactylation, and inhibits glycolysis. (R)-GNE-140 attenuates cardiac hypertrophy, alleviates PM2.5-induced pulmonary inflammation and fibrosis, blocks MRSA-induced Arg1 expression. (R)-GNE-140 is applicable to research related to pathological cardiac hypertrophy, pulmonary fibrosis, MRSA infection and pancreatic cancer .
loading...
    loading...
12
12 Cited Publications
Cat. No.: HY-101444A
CAS No.: 100929-99-5
Purity:  99.89%
Synonyms: MC-207,110 dihydrochloride; Phe-Arg-β-naphthylamide dihydrochloride
Target:  

Bacterial

Research Areas:  

Infection

PAβN dihydrochloride (MC-207110 dihydrochloride) is an efflux pump inhibitor.
loading...
    loading...
11
11 Cited Publications
Cat. No.: HY-P0019
CAS No.: 66216-78-2
Research Areas:  

Cardiovascular Disease

Z-Gly-Gly-Arg-AMC is a thrombin-specific fluorogenic substrate for testing of thrombin generation in PRP and platelet-poor plasma (PPP) (Ex/Em = 390/480 nm) .
loading...
    loading...
11
11 Cited Publications
Cat. No.: HY-P0019A
CAS No.: 2070009-61-7
Research Areas:  

Others

Z-Gly-Gly-Arg-AMC acetate is a thrombin-specific fluorogenic substrate for testing of thrombin generation in PRP and platelet-poor plasma (PPP) (Ex/Em = 390/480 nm) .
loading...
    loading...
10
10 Cited Publications
Cat. No.: HY-P0049
CAS No.: 113-79-1
Synonyms: Arg8-vasopressin; AVP
Target:  

Vasopressin Receptor

Research Areas:  

Neurological Disease Cancer

Argipressin (Arg8-vasopressin) binds to the V1, V2, V3-vascular arginine vasopressin receptor, with a Kd value of 1.31 nM in A7r5 rat aortic smooth muscle cells for V1.
loading...
    loading...
10
10 Cited Publications
Cat. No.: HY-W539944
CAS No.: 129979-57-3
Synonyms: Arg8-vasopressin acetate; AVP acetate
Research Areas:  

Neurological Disease Cancer

Argipressin (Arg8-vasopressin) (acetate) binds to the V1, V2, V3-vascular arginine vasopressin receptor, with a Kd value of 1.31 nM in A7r5 rat aortic smooth muscle cells for V1 .
loading...
    loading...
9
9 Cited Publications
Cat. No.: HY-12290
CAS No.: 91037-65-9
Purity:  99.93%
Synonyms: RGDS peptide; Fibronectin tetrapeptide
Target:  

Integrin

Research Areas:  

Inflammation/Immunology

Arg-Gly-Asp-Ser is an integrin binding sequence that inhibits integrin receptor function. Arg-Gly-Asp-Ser directly and specifically bind pro-caspase-8, pro-caspase-9 and pro-caspase-3, while it does not bind pro-caspase-1.
loading...
    loading...
7
7 Cited Publications
Cat. No.: HY-112885B
CAS No.: 2250019-93-1
Purity:  99.96%
Synonyms: Nω-Hydroxy-nor-L-arginine monoacetate
nor-NOHA monoacetate is a selective and reversible arginase inhibitor. nor-NOHA monoacetate induces apoptosis in ARG2-expressing cells under hypoxia. nor-NOHA monoacetate has anti-leukemic activity. nor-NOHA monoacetate can used in study of endothelial dysfunction, immunosuppression and metabolism .
loading...
    loading...
7
7 Cited Publications
Cat. No.: HY-112885A
CAS No.: 1140844-63-8
Purity:  98.81%
Synonyms: Nω-Hydroxy-nor-L-arginine acetate
nor-NOHA acetate is a selective and reversible Arginase inhibitor. nor-NOHA acetate induces Apoptosis in ARG2-expressing cells under hypoxia. nor-NOHA acetate has anti-leukemic activity. nor-NOHA acetate improves liver ischemia-reperfusion injury. nor-NOHA acetate can used in study of tuberculosis, endothelial dysfunction, immunosuppression and metabolism .
loading...
    loading...
7
7 Cited Publications
Cat. No.: HY-112885C
CAS No.: 291758-32-2
Purity:  98.85%
Synonyms: Nω-Hydroxy-nor-L-arginine dihydrochloride
nor-NOHA dihydrochloride is a selective and reversible Arginase inhibitor. nor-NOHA dihydrochloride induces Apoptosis in ARG2-expressing cells under hypoxia. nor-NOHA dihydrochloride has anti-leukemic activity. nor-NOHA dihydrochloride improves liver ischemia-reperfusion injury. nor-NOHA dihydrochloride can used in study of tuberculosis, endothelial dysfunction, immunosuppression and metabolism .
loading...
    loading...
3
3 Cited Publications
Cat. No.: HY-P0074A
CAS No.: 157009-81-9
Synonyms: Gly-Pro-Arg-Pro acetate; Pefa 6003 acetate
Target:  

Integrin

Research Areas:  

Cardiovascular Disease

GPRP acetate (Gly-Pro-Arg-Pro acetate) is a fibrin polymerization inhibitor that inhibits the interaction of fibrinogen with the platelet membrane glycoprotein IIb/IIIa complex (GPIIb/IIIa) .
loading...
    loading...
3
3 Cited Publications
Cat. No.: HY-P0074
CAS No.: 67869-62-9
Synonyms: Gly-Pro-Arg-Pro; Pefa 6003
Target:  

Thrombin

Research Areas:  

Cardiovascular Disease

GPRP (Gly-Pro-Arg-Pro; Pefa 6003) is a fibrin polymerization inhibitor that inhibits the interaction between fibrinogen and the platelet membrane glycoprotein Ⅱb/IIIa complex (glycoprotein IIb/IIIa receptor) . GPRP increases the level of free thrombin in activated platelet-rich plasma by reducing the adsorption of thrombin onto fibrin. GPRP inhibits platelet aggregation and prolongs the thrombin-initiated clotting time in plasma. GPRP is applicable for research related to thrombosis and thrombotic diseases .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-134434
CAS No.: 136132-67-7
Purity:  99.79%
Research Areas:  

Others

Z-Arg-Arg-AMC hydrochloride is a highly selective fluorescent Cathepsin B substrate. Z-Arg-Arg-AMC hydrochloride can be hydrolyzed by Cathepsin B to produce a fluorescent product for enzyme activity detection .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-112862
CAS No.: 301351-95-1
Purity:  ≥98.0%
Research Areas:  

Infection

Arg-AMS (compound 24) is a potent nanomolar inhibitor of arginyl tRNA synthetase, which displays tightly bound inhibitory characteristics for the A-domains in non-ribosomal peptide synthetases (NRPS) enzymes .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-P2300
CAS No.: 862772-11-0
Synonyms: Cyclo(RGDfC)
Target:  

Integrin

Research Areas:  

Cancer

Cyclo(Arg-Gly-Asp-D-Phe-Cys) (Cyclo RGDfC), a cyclic RGD peptide which has high affinity to αvβ3, can disrupt cell integrin interactions. Cyclo(Arg-Gly-Asp-D-Phe-Cys) inhibits pluripotent marker expression in embryonic stem cells (ESCs) and the tumorigenic potential of mESCs in vivo. Cyclo(Arg-Gly-Asp-D-Phe-Cys) can be used in the research of tumors .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-P2300A
Synonyms: Cyclo(RGDfC) TFA
Target:  

Integrin

Research Areas:  

Cancer

Cyclo(Arg-Gly-Asp-D-Phe-Cys) (Cyclo RGDfC) TFA, a cyclic RGD peptide which has high affinity to αvβ3, can disrupt cell integrin interactions. Cyclo(Arg-Gly-Asp-D-Phe-Cys) TFA inhibits pluripotent marker expression in embryonic stem cells (ESCs) and the tumorigenic potential of mESCs in vivo. Cyclo(Arg-Gly-Asp-D-Phe-Cys) TFA can be used in the research of tumors .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-W016781
CAS No.: 157-06-2
Synonyms: H-D-Arg-OH
D-arginine (H-D-Arg-OH) is the D-isomer of arginine. Arginine is an α-amino acid that is used in the biosynthesis of proteins. D-Arginine is an inactive form of L-arginine. D-arginine can be used in myeloma and neurological disease research . .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-P2381
CAS No.: 2410957-04-7
Target:  

Angiotensin Receptor

Research Areas:  

Others

Sar-Arg-Val-Tyr-Val-His-NH2 is a Gq-biased agonists, exhibits 10-fold larger molecular efficacies at the AT1R-Gq fusion protein compared with the AT1R-βarr2 fusion protein .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-N2369
CAS No.: 476-32-4
Chelidonine, an isoquinoline alkaloid, can be isolated from Chelidonium majus L.. Chelidonine causes G2/M arrest and induces caspase-dependent and caspase-independent apoptosis, and prevents cell cycle progression of stem cells in Dugesia japonica. Chelidonine has cytotoxic activity against melanoma cell lines. with anticancer and antiviral activity .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-P4931
CAS No.: 720710-69-0
Target:  

MMP

Research Areas:  

Cancer

Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 (FS-6) is a fluorescent peptide that is a quenched MMP peptide substrate. Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 can be used for real-time quantification of MMP enzymatic activity. Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 is an elongated peptide of MMP substrate (FS-1) and is active against collagenases (MMP-1, MMP-8, MMP-13 ) and MT1-MMP with higher specificity constants than FS-1 . (Ex/Em=325 nm/400 nm)
loading...
    loading...